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. Author manuscript; available in PMC: 2014 Dec 5.
Published in final edited form as: Circ Heart Fail. 2011 Jan 12;4(2):153–160. doi: 10.1161/CIRCHEARTFAILURE.110.957829

Table 2. Multivariable Model of Predictors of Early (6-month) Death or Re-transplant in Heart Transplant Recipients.

Predictor Hazard Ratio 95% Confidence Interval P Value
Age at Transplant ** ** <0.001
Recipient Height ** ** <0.001
Donor Age ** ** <0.001
Diagnosis (vs. Dilated CM)
 Ischemic CM 1.22 (1.14, 1.31) <0.001
 Hypertrophic CM 1.36 (1.02, 1.81) 0.04
 Congenital Heart Disease 2.69 (2.25, 3.22) <0.001
 Other 1.29 (1.13, 1.47) <0.001
Drug Treated 1.14 (1.06, 1.23) 0.001
Hypertension
Mean PAP > 30 mmHg 1.08 (1.00, 1.16) 0.06
PVR < 3 0.89 (0.82, 0.96) 0.002
Mechanical Ventilation 2.41 (2.12, 2.73) <0.001
Intra-aortic Balloon Pump 1.21 (1.08, 1.36) 0.001
VAD 1.57 (1.44, 1.72) <0.001
ECMO 2.10 (1.44, 3.08) <0.001
ICD 1.09 (1.00, 1.19) 0.06
Ischemic Time ** ** 0.001
PRA
 > 10% 1.22 (1.11, 1.33) <0.001
 Missing 1.01 (0.94, 1.09) 0.81
Bilirubin at Transplant ** ** 0.001
IV Antibiotic <2 Weeks Before Transplant Gender Match* 1.24 (1.12, 1.38) <0.001
 M recipient / F donor 1.20 (1.11, 1.30) <0.001
 F recipient / M donor 1.11 (0.99, 1.25) 0.06
 F recipient / F donor 1.07 (0.96, 1.20) 0.24
Medicaid Insurance 1.12 (1.00, 1.25) 0.06
Era (treated as linear 1-5) 0.83 (0.80, 0.87) <0.001
Race (vs. White)
 Black 1.15 (1.05, 1.26) 0.004
 Hispanic 1.03 (0.90, 1.18) 0.66
**

Restricted cubic splines, with a separate term to identify missing values if required. CM (Cardiomyopathy), PAP (Pulmonary Artery Pressure), PVR (Pulmonary Vascular Resistance), ECMO (Extra-corporeal Membrane Oxygenation), ICD (Implantable Cardioverter Defibrillator), VAD (Ventricular Assist Device), hr (hour), IV (intravenous), PRA (Panel Reactive Antibodies),

*

The reference category is M recipient-M donor. The donor-recipient BMI ratio or donor LV ejection fraction was not significant.