Table 3. Multivariable Model of Predictors for Time to Graft Loss in 6-Month Survivors of Heart Transplantation.

Predictor	Hazard Ratio	95% CI	P Value
Age at Transplant	**	**	<0.001
Donor Age	**	**	<0.001
Diagnosis (vs. Dilated CM)
Ischemic CM	1.22	(1.17, 1.27)	<0.001
Hypertrophic CM	0.75	(0.59, 0.94)	0.01
Congenital Heart Disease	0.88	(0.75, 1.03)	0.11
Other	1.03	(0.95, 1.12)	0.52
Drug Treated Hypertension	1.04	(0.98, 1.09)	0.20
Diabetes
Yes	1.19	(1.12, 1.27)	<0.001
Not reported	1.16	(1.09, 1.24)	<0.001
VAD	0.95	(0.88, 1.02)	0.16
ICD	0.90	(0.85, 0.96)	0.001
Creatinine at Transplant
> 1.5	1.20	(1.13, 1.26)	<0.001
Not reported	1.08	(1.02, 1.14)	0.008
IV Antibiotic <2 Weeks Before Transplant	1.14	(1.05, 1.24)	0.002
Medicaid Insurance	1.43	(1.33, 1.54)	<0.001
Interaction: Era by Race†
White	0.95	(0.92, 0.97)	<0.001
Black	1.04	(0.99, 1.09)	0.07
Hispanic	1.02	(0.95, 1.09)	0.63

^**Restricted cubic splines, with a separate term to identify missing values if required.

^†Race-era interaction terms were interpreted in two ways, as era effect within racial groups (above) and as racial differences in outcomes within all eras (Figure 2). CM (Cardiomyopathy), ICD (Implantable Cardioverter Defibrillator), VAD (Ventricular Assist Device), IV (intravenous)