Table 2.
Graft Characteristics According to Treatment Group among Patients Who Underwent Transplantation.*
| Characteristic | Double-Unit Treatment Group (N = 108) | Single-Unit Treatment Group (N = 112) | ||
|---|---|---|---|---|
| Unit A | Unit B | Combined | ||
|
| ||||
| HLA match score — no. of patients (%) | ||||
|
| ||||
| 3/6 | 2 (2) | 1 (1) | 2 (2)† | 1 (1) |
|
| ||||
| 4/6 | 33 (31) | 43 (40) | 48 (44)† | 44 (39) |
|
| ||||
| 5/6 | 59 (55) | 43 (40) | 46 (43)† | 51 (46) |
|
| ||||
| 6/6 | 14 (13) | 21 (19) | 12 (11)† | 16 (14) |
|
| ||||
| Cell dose — cells/kg | ||||
|
| ||||
| Cryopreserved total nucleated cells | 5.0×107±3.1×107 | 4.1×107±3.5×107 | 9.1×107 | 4.8×107±3.4×107 |
|
| ||||
| Infused total nucleated cells | 4.0×107±3.0×107 | 3.2×107±3.4×107 | 7.2×107 | 3.9×107±3.0×107 |
|
| ||||
| Cryopreserved CD34+ cells | 2.0×105±2.2×105 | 1.8×105±1.4×105 | 3.7×105 | 1.9×105±3.6×105 |
|
| ||||
| ABO match — no. of patients (%) | ||||
|
| ||||
| Major mismatch | 25 (23) | 31 (29) | — | 30 (27) |
|
| ||||
| Minor mismatch | 35 (32) | 29 (27) | — | 24 (21) |
|
| ||||
| Bidirectional mismatch | 8 (7) | 4 (4) | — | 10 (9) |
|
| ||||
| No mismatch | 36 (33) | 38 (35) | — | 44 (39) |
|
| ||||
| Unknown | 4 (4) | 6 (6) | — | 4 (4) |
*
Plus–minus values are means ± SD. Percentages may not add to 100 because of rounding.
†
The combined match score for patients in the double-unit treatment group is the minimum HLA match between the first unit and the recipient or the second unit and the recipient. For example, if Unit A was a 6/6 match with the recipient and Unit B was a 4/6 match, the match score assigned for that recipient was 4/6.