Table 1.
Minimal inhibitory concentrations of K20 and kanamycinA against bacteria and fungi.
| Organism | MIC (mg/L)a | |||
|---|---|---|---|---|
| K20 | Kanamycin | ITC | FLC | |
| YEASTS | ||||
| C. neoformans H99 | 3.9–7.8 | >125b | 1.56 | 1.56 |
| C. neoformans 94-2586 | 3.9–7.8 | >125b | 0.06 | 1.56 |
| C.neoformans 90-26 | 3.9–7.8 | >250 | 0.37 | >0.195 |
| C. pseudotropicalis YOGI | 15.6 | >250 | 0.125–0.8 | ndc |
| C. lusitaniae 95-767 | >7.8 | >250 | 0.2 | 1.56 |
| C. rugosa 95-967 | 15.6 | >250 | 0.12 | >0.78 |
| C. tropicalis 95-41 | 15.6 | >250b | >25 | >25 |
| C. albicans 10231 | 15.6 | >250b | 0.75 | 25 |
| C. albicans 64124(R)d | 31.3 | >500b | >64 | >200 |
| C. albicans MYA 2876 (S)e | 15.6 | >250 | >2 | 1.56 |
| C. albicans B-311 | >7.8 | >250 | 16–32 | >25 |
| C. albicans 94-2181 | >7.8 | >250 | >8–16 | >12.5 |
| C. parapsilosis (R)d | 15.6–31.3 | >250 | 0.5 | >16 |
| C. parapsilosis (S)e | 15.6 | >250 | 0.015 | 0.12 |
| FILAMENTOUS FUNGI | ||||
| F. graminearum B-4-5A | 7.8 | >125b | nd | nd |
| F. oxysporum | 31.3 | >250b | nd | nd |
| A. flavus | 300 | >250 | 0.125 | nd |
| A. niger | >150 | >250 | nd | nd |
| B. alcada | 15.6 | nd | ||
| BACTERIA | ||||
| E. coli TG1 | 125–250 | 1.95b | ||
| S. aureus ATCC 25923 | 250 | <0.98b | ||
| M. luteus ATCC10240 | 62.5 | 1.95b | ||
a
Microbroth dilution assays were performed at least twice, and each in triplicate.
b
Determined with kanamycin A; all others were determined with kanamycin B.
c
not determined.
d
(R) Resistant.
e
(S) Sensitive.