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K20 susceptibilities of Saccharomyces cerevisiae sphingolipid biosynthesis mutantsa.
| Strain and genotype | MIC (mg/L)b |
|---|---|
| W303C (MATα ade2 his3 leu2 trp1 ura3) | 15.6 |
| W303-Δsyr2 (MATα ade2 his3 leu2 trp1 ura3 syr2 (sur2)::URA3) | 62.5 |
| W303-Δelo3 (MATα ade2 his3 leu2 trp1 ura3 elo2::HIS3) | 31.3 |
| W303-Δsyr4 (ipt1)(MATα ade2 his3 leu2 trp1 ura3 syr4 (ipt1)::URA3 | 15.6 |
Values are average of three assay determinations.
Microbroth dilution assays were conducted in RPMI 1640 medium.
