Table 2.
Cytokine | Frequency of alcohol use | P‐valuea | Ethanol consumed per day | P‐valuea | Alcohol‐use disorder | P‐valuea | Abstinence duration | P‐valuea | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
≤3 days per week | ≥4 days per week | <10 units | ≥10 units | Alcohol abuse | Alcohol dependence | <10 days | ≥10 days | |||||
IL‐6 | 8.07 (7.39/10.6) | 9.1 (7.19/10.8) | 0.079 | 8.63 (7.23/10.6) | 8.91 (6.91/10.9) | 0.352 | 8.14 (7.25/10) | 9.10 (7.27/10.9) | 0.317 | 8.36 (6.48/11.4) | 8.91 (7.6/10.8) | 0.249 |
TNF‐α | 31.9 (24.6/40) | 31.9 (25.3/40) | 0.389 | 31.9 (26.9/39.6) | 32.3 (25.6/40.4) | 0.620 | 30.7 (20.5/36.6) | 32.6 (25/40.4) | 0.454 | 33.1 (23.2/40) | 31.9 (25.3/40) | 0.600 |
IFN‐γ | 86.4 (67.9/125) | 98.4 (74.6/118) | 0.026 | 90.1 (71.2/113) | 93.5 (70.6/123) | 0.826 | 80.4 (66.4/102) | 95.4 (71.2/124) | 0.313 | 83.4 (60.4/124) | 98.9 (77.3/119) | 0.095 |
IL‐10 | 9 (5.31/10.6) | 9.35 (6.91/12.2) | 0.005 | 8.41 (5.31/10.7) | 9.35 (6.91/12.2) | 0.024 | 7.59 (6.73/10.5) | 9.35 (6.27/11.9) | 0.746 | 9.18 (4.75/12.3) | 9.35 (7.04/11.8) | 0.157 |
P‐values were calculated by Mann–Whitney U‐test. Significant values are shown in bold.