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. 2014 Jul 3;20(10):898–904. doi: 10.1111/cns.12303

Table 2.

Alcohol‐use characteristics and their relationship with cytokine levels. Results are expressed as median values with 25/75 percentiles

Cytokine Frequency of alcohol use P‐valuea Ethanol consumed per day P‐valuea Alcohol‐use disorder P‐valuea Abstinence duration P‐valuea
≤3 days per week ≥4 days per week <10 units ≥10 units Alcohol abuse Alcohol dependence <10 days ≥10 days
IL‐6 8.07 (7.39/10.6) 9.1 (7.19/10.8) 0.079 8.63 (7.23/10.6) 8.91 (6.91/10.9) 0.352 8.14 (7.25/10) 9.10 (7.27/10.9) 0.317 8.36 (6.48/11.4) 8.91 (7.6/10.8) 0.249
TNF‐α 31.9 (24.6/40) 31.9 (25.3/40) 0.389 31.9 (26.9/39.6) 32.3 (25.6/40.4) 0.620 30.7 (20.5/36.6) 32.6 (25/40.4) 0.454 33.1 (23.2/40) 31.9 (25.3/40) 0.600
IFN‐γ 86.4 (67.9/125) 98.4 (74.6/118) 0.026 90.1 (71.2/113) 93.5 (70.6/123) 0.826 80.4 (66.4/102) 95.4 (71.2/124) 0.313 83.4 (60.4/124) 98.9 (77.3/119) 0.095
IL‐10 9 (5.31/10.6) 9.35 (6.91/12.2) 0.005 8.41 (5.31/10.7) 9.35 (6.91/12.2) 0.024 7.59 (6.73/10.5) 9.35 (6.27/11.9) 0.746 9.18 (4.75/12.3) 9.35 (7.04/11.8) 0.157
a

P‐values were calculated by Mann–Whitney U‐test. Significant values are shown in bold.