Figure 5.

Urethral reconstruction using cell-seeded dHAS in a rabbit urethral injury model. (A) Urethral reconstruction surgery utilizing a cell-seeded dHAS patch. (B) immunohistochemical evaluation of CD4⁺ and CD8⁺ infiltrations 2 weeks after urethroplasty. Significant accumulation of CD4⁺ cells and CD8⁺ cells in the dHAS group were found (^* P<0.05); (C) HE staining of cell-seeded dHAS graft 2 weeks after surgery. The graft was intact without obvious infiltration of inflammatory cells. The continuity of epithelial cells was recovered (magnification at ×200); (D) HE staining of dHAS patch 2 weeks after surgery revealed serious inflammatory infiltration (magnification at ×200).