Table 2. Calcium, phosphorus and pyrophosphate concentrations in serum/plasma of mice maintained on a regular rodent diet.
| Parameter | Concentration (mean ± S.E.) | ||
| Enpp1+/+ (n = 8) | Enpp1+/asj-2J (n = 11) | Enpp1asj-2J (n = 12) | |
| Calcium (mg/dL) | 9.38±0.18 | 9.52±0.15 | 9.41±0.17 |
| Phosphorus (mg/dL) | 9.32±0.32 | 9.30±0.31 | 9.37±0.24 |
| Ca/P ratio | 1.01±0.03 | 1.03±0.03 | 1.01±0.03 |
| PPi (µM) | 2.53±0.44 | 1.78±0.23 | 0.52±0.08* |
| PPi/Pi ratio (×1,000) | 4.22±0.74 | 2.96±0.38 | 0.88±0.12* |
Blood samples were collected by cardiac puncture, Ca and P concentrations were determined in serum, and PPi levels were measured in heparinized plasma after removal of platelets. Statistical significance in comparison to Enpp1+/+ mice: *P<0.01.