Table 7.
Simulated Cmax values at steady state in the healthy population after multiple administrations of 5–20 mg vortioxetine
Dose (mg/day) | Mean (ng/mL) | Median (ng/mL) | S.D. (ng/mL) | 95% PI (ng/mL) |
---|---|---|---|---|
5 | 7.2 | 7.1 | 4.3 | 3.1;17.4 |
10 | 14.4 | 14.2 | 8.5 | 6.1;34.9 |
15 | 21.6 | 21.4 | 12.8 | 9.2;52.3 |
20 | 28.8 | 28.5 | 17.0 | 12.3;69.8 |
S.D., standard deviation; PI, prediction interval.