Table 5. Odds ratios for carotid atherosclerosis by serum bilirubin quartiles within each gender.

	Men N = 325					Women N = 509
Characteristics	N	Non-adjusted odds ratio (95%CI)	P-value	Multivariate-adjustedodds ratio (95%CI)§	P-value	N	Non-adjusted odds ratio (95%CI)	P-value	Multivariate-adjusted odds ratio (95%CI)§	P-value
Carotid IMT ≥1.0 mm including plaque
Quartile-1	88	1.00		1.00		121	1.00		1.00
Quartile-2	75	0.40 (0.16–1.01)	0.051	0.38 (0.14–1.06)	0.065	128	0.35 (0.18–0.65)	0.001	0.40 (0.20–0.83)	0.013
Quartile-3	79	0.43 (0.17–1.07)	0.069	0.43 (0.15–1.20)	0.107	130	0.65 (0.34–1.28)	0.213	0.61 (0.29–1.30)	0.201
Quartile-4	83	0.28 (0.12–0.67)	0.004	0.29 (0.11–0.77)	0.013	130	0.38 (0.20–0.72)	0.003	0.43 (0.21–0.89)	0.022
Carotid plaque
Quartile-1	88	1.00		1.00		121	1.00		1.00
Quartile-2	75	0.55 (0.25–1.21)	0.138	0.47 (0.19–1.15)	0.097	128	0.37 (0.21–0.66)	0.001	0.41 (0.21–0.78)	0.007
Quartile-3	79	0.59 (0.27–1.29)	0.186	0.53 (0.21–1.31)	0.169	130	0.56 (0.31–1.02)	0.057	0.51 (0.26–0.98)	0.045
Quartile-4	83	0.26 (0.13–0.55)	<0.001	0.25 (0.11–0.57)	0.001	130	0.41 (0.23–0.73)	0.003	0.46 (0.24–0.89)	0.021

CI, confidence interval. § Adjusted for confounding factors in model 1 of Table 4 by stepwise multiple logistic regression analysis. Subjects were divided into four groups based on quartile of serum bilirubin (men, Quartile-1, 0.13–0.54; Quartile-2, 0.55–0.73; Quartile-3, 0.74–1.02; Quartile-4, 1.03–2.00 mg/dL and women, Quartile-1, 0.21–0.51; Quartile-2, 0.52–0.67; Quartile-3, 0.68–0.88; Quartile-4, 0.89–2.00 mg/dL).