Figure 6.
H2O–D2O exchange kinetics in (a) rat sciatic nerves, (b) rat optic nerves, (c) mouse sciatic nerves and (d) mouse spinal cords. Samples equilibrated against 100% D2O-saline were first perfused with 20% D2O-saline (t = 0), followed by a perfusion with 100% D2O-saline (arrow) once equilibrium was reached. The extent of exchange is indicated by the change in intensity of the second-order reflection over time. Long periods with no change are indicated by breaks in the x axis. Curves behind the data points represent double-exponential decay models fitted to the data.