Table 8.
Study 2 (Sudan): sensitivity, specificity, PPV, and NPV for DAT and four improved rK28 RDTs*
| Test | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| Percentage (95% confidence interval) | ||||
| DAT | 95.0 (88.7–98.3) | 100 (97.5–100) | 95.0 (96.1–100) | 96.7 (92.6–98.9) |
| DPP | 95.0 (88.7–98.3) | 96.0 (91.5–98.5) | 94.0 (87.5–97.7) | 96.6 (92.3–98.9) |
| CTK | 94.0 (87.4–97.7) | 99.3 (96.3–99.9) | 98.9 (94.2–99.9) | 96.1 (917–98.5) |
| EMT | 97.0 (91.4–99.3) | 91.3 (85.6–95.3) | 88.1 (80.6–93.5) | 97.8 (93.8–99.5) |
| InBios+ | 96.0 (90.0–98.9) | 92.7 (87.2–96.2) | 89.7 (82.3–94.7) | 97.2 (92.9–99.2) |
*
Note: visceral leishmaniasis (VL) negative control panel consists of HNEC and OD.
PPV = positive predictive value; NPV = negative predictive value; DAT = direct agglutination test; RDTs = rapid diagnostic tests; DPP = dual path platform; EMT = EASE-Medtrend test.