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. 2014 Dec 5;9(12):e114556. doi: 10.1371/journal.pone.0114556

Table 1. Correlation between NKX2.1 expression and clinicopathological variables of 205 gastric cancer cases.

Clinicopathological parameters n a NKX2.1 Expression χ2 P Value
Low High
All 205 87 118
Age (years)
<55 84 25 59 9.363 0.002*
≥55 121 62 59
Gender 0.031 0.861
Male 74 32 42
Female 131 55 76
Tumor size 8.088 0.004*
<3 cm 40 9 31
≥3 cm 165 78 87
Tumor infiltration 24.503 <0.001*
T1 32 5 27
T2 22 3 19
T3 16 9 7
T4a 104 51 53
T4b 31 19 12
Local lymph node metastasis 3.468 0.325
N0 66 24 42
N1 38 19 19
N2 39 14 25
N3 62 30 32
Distant metastasis 0.257 0.612
M0 184 77 107
M1 21 10 11
TNM staging 21.330 <0.001*
I 42 5 37
II 38 22 16
III 104 50 54
IV 21 10 11
a

Numbers of cases in each group.

*Statistically significant (P<0.05).