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. 2014 Dec 5;9(12):e114240. doi: 10.1371/journal.pone.0114240

Figure 1. Manhattan plot of genome-wide association study of decline of eGFR.

Figure 1

SNPs were characterized using the Illumina Cardio-Metabo Chip. After frequency and genotyping pruning, there were 124215 SNPs left. Highest association was seen in rs17069906 (p = 5.63 e-10), rs9812824 (p = 6.53 e-8), and rs9588431 (p = 3.57 e-7).The red line indicates genome-wide significant associations (4.02 e-7).SNPs are associated with decline of eGFR independently from baseline eGFR.