Table 3. Brain Regions of Relative Hypometabolism Associated with the Existence of Hallucinations (Hypo), and Brain Regions of Relative Hypermetabolism Associated with the Existence of Hallucinations (Hyper).

							Coordinates MNI (mm)
	Brain Regions	BA Vicinity	Side	No. Voxels	T value	x	y	z	p
Hypo	Frontal lobe, inferior, middle frontal gyrus (orbital), and insula (ant)	45/47/44/10/9	R	3625	4.56	46	25	2	0.000031
Hyper	Frontal lobe, superior frontal gyrus	6	L	347	4.52	−24	−11	69	0.000036
	Temporal lobe, fusiform gyrus	37	L	91	3.92	27	−41	−20	0.00020
	Parietal lobe, postcentral gyrus and precuneus	7	L L	90	3.79	−15	−53	74	0.00029
	Parietal lobe, postcentral and supramarginal gyri	40		353	3.71	−51	−21	33	0.00037

T = p<0.001, uncorrected, minimum cluster size = 25 voxels; ant = anterior; BA = Brodmann's area; L = left; R = right; NA = not applicable; No. = number.

Underlined brain regions are “core regions” of hallucinations in AD (see Methods).