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Changes in the percentage (A) and absolute number (B) of naive B-cells according to age. The proportions of naive B-cells (CD27− IgD+) (A) among CD19+ lymphocytes were analyzed by flow cytometry on whole-blood samples. The corresponding absolute numbers (B) were calculated from the absolute number of B-cells. Solid horizontal lines indicate the median values for each age group. m = month; y = year.
