Table 3.
Absolute numbers of B-cell subsets by age group (/µL blood)
| Age no. of individuals | 0–1 m (n = 14) | 1–6 m (n = 19) | 6–18 m (n = 37) | 18 m–4 y (n = 37) | 4–8 y (n = 36) | 8–12 y (n = 36) | 12–18 y (n = 63) |
|---|---|---|---|---|---|---|---|
| Lymphocytes | 3,922 (2,195–6,218) | 5,800 (3,944–8,030) | 4,791 (3,297–7,820) | 3,900 (2,373–7,249) | 2,810 (1,761–3,873) | 2,209 (1,445–3,725) | 2,057 (1,379–3,663) |
| CD19+ | 292 (24–580) | 1,121 (712–2,059) | 1,300 (523–2,149) | 759 (319–1,244) | 504 (273–860) | 336 (219–509) | 340 (193–628) |
| CD19+CD27+ | 8 (1–29) | 42 (13–85) | 91 (25–217) | 107 (45–175) | 80 (23–185) | 54 (31–152) | 57 (26–115) |
| CD27− IgD+ | 271 (23–553) | 1,080 (677–1,968) | 1,161 (461–1,930) | 607 (212–1,027) | 342 (203–648) | 241 (128–403) | 254 (126–546) |
| CD27− IgD− | 2 (0–17) | 11 (3–31) | 11 (4–28) | 20 (10–56) | 23 (8–74) | 18 (7–35) | 16 (6–42) |
| CD27+IgD+ | 6 (1–27) | 30 (13–78) | 66 (14–170) | 63 (23–113) | 40 (7–91) | 25 (8–81) | 20 (7–56) |
| CD27+ IgD− | 1 (0–4) | 6 (1–13) | 19 (7–57) | 48 (20–93) | 42 (11–103) | 34 (13–72) | 33 (12–69) |
The absolute numbers of lymphocytes, total CD19+ B-cells and of each B-cell subset per µL blood are shown for each age group, as medians (upper line) and as the corresponding 5th and 95th percentiles (lower line). m = months; y = years.