Table. Clinical progression for cats in experimental equine influenza A(H3N8) virus inoculation study* .
Cohort, cat |
No. days after inoculation |
|||||||||||||||
–1 |
0 |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
13 |
14 |
|
Inoculated | ||||||||||||||||
A1 | 0 | 0 | 0 | 2 | 2.5 | 3.5 | 0.5 | † | ||||||||
A2 | 0 | 0 | 0.5 | 2.5 | 2.5 | 3 | 2 | 1.5 | 0.5 | 0.5 | 0.5 | 0 | 0 | 0 | 0 | 0 |
A3 | 0 | 0 | 0 | 2 | 2.5 | 2.5 | 2 | 0.5 | 0 | † | ||||||
A4 | 0 | 0 | 1 | 2 | 2 | 2.5 | 1.5 | 0.5 | 0.5 | † | ||||||
A5 | 0 | 0 | 0 | 2 | 2.5 | 3 | 2 | † | ||||||||
A6 |
0 |
0 |
0 |
2.5 |
3 |
3 |
1 |
1.5 |
1.5 |
0.5 |
0 |
0 |
0 |
0 |
0 |
0 |
Contact | ||||||||||||||||
B1 | 0 | 0 | 0 | 0 | 0 | 0 | 2.5 | 3 | 2.5 | † | ||||||
B2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.5 | 0 | 0 | 0 | 0 | 0 | 0 |
B3 | 0 | 0 | 0 | 0 | 0 | 1.5 | 2.5 | 1.5 | 1.5 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
B4 | 0 | 0 | 0 | 0 | 0 | 0.5 | 3 | 2.5 | 1.5 | † | ||||||
B5 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0.5 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
Control | ||||||||||||||||
C1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
C2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
C3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
*Data indicate the sum of clinical scores, as follows: ocular and nasal discharge (0 = no discharge, 0.5 = serous, 1.0 = mild mucopurulent, 2.0 = severe mucopurulent); cough (0 = absent, 0.5 = mild, 1.0 = moderate, 1.5 = persistent, 2.0 = severe with choking or retching); sneezing, dyspnea, and depression (0 = absent, 2 = present); and body temperature (0 = <39.58°C, 2 = ≥39.58°C). Shading indicates days on which some animals had a clinical score >1, showing the shift between the 2 cohorts. †Euthanized on the day indicated.