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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: J Biochem Mol Toxicol. 2014 Aug 6;28(12):529–538. doi: 10.1002/jbt.21594

FIGURE 2.

FIGURE 2

Antioxidants (VC and Res) significantly reverse E2-mediated decrease in Nrf2 mRNA and protein expression levels in MCF-10A cells. (A) Nrf2 mRNA expression levels in MCF-10A cells treated with 50 nM E2, 50 μM Res, Res + E2, 1 mM VC or VC + E2 for 24 hr and (B) Nrf2 protein expression levels in MCF-10A cells treated with 50 nM E2, 50 μM Res, Res + E2, 1 mM VC or VC + E2 for up to 48 hr.

‘*’ indicates p value ≤ 0.05 compared with respective controls.