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. 2014 Aug 19;25(2):171–181. doi: 10.1111/bpa.12165

Figure 2.

figure

Nicotinic acetylcholine receptors (nAChRs) and 5‐hydroxytryptamine (5‐HT) markers in the fetal baboon occipital lobe. Pseudocolored autoradiographic images of (A) 3 H‐epibatidine binding to α2‐4, β2, β4 nAChRs, (B) 125 I‐bungrotoxin binding to α7 nAChRs, (C) 3 H‐8‐OH‐DPAT binding to 5‐HT 1A receptors, (D) 125 I‐DOI binding to 5‐HT 2A receptors, and (E) 125 I‐RTI‐55 binding to the 5‐HT transporter in the fetal baboon occipital lobe with specific activity scales for control (left) and nicotine‐exposed (right) fetuses with corresponding graphs of binding levels for each group (fmol/mg tissue). Nicotine exposure resulted in a region‐specific increase in 3 H‐epibatidine binding (B). *P < 0.05, mean of means ± standard error of the mean. Legend: Brodmann area (BA) 17: primary visual cortex, BAs 18 and 19: associated visual cortices.