Table 2.
ESRS | Week 0 (N = 20) | Week 1 (N = 20) | Week 2 (N = 20) | Week 4 (N = 19 + 1 LOCF) | Week 6 (N = 20) | Week 8 (N = 20) | Week 12 (N = 18 + 2 LOCF) | F or χ2 statistic | df | p |
---|---|---|---|---|---|---|---|---|---|---|
Total score | 24 (12.5) | 23.4 (12.9) | 24.3 (13.0) | 23.9 (13.3) | 23.6 (13.5) | 25.5 (15.7) | 24.4 (12.1) | F = 0.492 | 6, 114 | 0.813 |
Parkinsonism | 9.1 (5.7) | 9.5 (6.0) | 9.25 (5.8) | 9.8 (6.3) | 9.2 (6.0) | 10.7 (6.5) | 9.7 (6.3) | F = 1.247 | 6, 114 | 0.288 |
Akathisia | 1.7 (1.8) | 1.6 (1.4) | 2.0 (1.8) | 1.7 (1.8) | 2.1 (1.7) | 1.8 (1.9) | 2.2 (1.7) | F = 0.827 | 6, 114 | 0.551 |
Dystonia | 0.8 (1.6) | 0.8 (1.6) | 0.8 (1.5) | 0.9 (1.6) | 0.7 (1.5) | 1.1 (1.7) | 0.8 (1.6) | χ2 = 7.114 | 6 | 0.310 |
Tardive dyskinesia | 3.6 (3.4) | 3.3 (3.6) | 3.6 (4.0) | 3.2 (3.5) | 3.2 (3.7) | 3.4 (3.9) | 3.4 (4.1) | χ2 = 3.764 | 6 | 0.709 |
ESRS, Extrapyramidal Symptoms Rating Scale; LOCF, last observation carried forward; SD, standard deviation.