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Hypothetical breakpoints (the dotted line) in rob(14;21), clones marked in green are present (based on FISH results) in mcROBs, while clones marked in red are absent. The breakpoints according to Lyle results and the hypothesis about opposite orientation of sequences on 14p than on 21p (a). Our PCR and FISH results indicate that the breakpoints are in/nearby to clone CR382332 in both (b) or only in one (c–d) chromosome involved in rob(14;21)
