Table 3.
Surgical Procedures and Post-Operative Outcomes for Hirschsprung’s Disease Cohort Before and After Propensity Score Matching (table)
| Variable, N (%) | Total Cohort | PS Matched Cohort | ||||||
|---|---|---|---|---|---|---|---|---|
| Total Cohort N=1555 | Single-Stage N=1201 | Multi-Stage N=354 | P | Total Cohort N=558 | Single-Stage N=279 | Multi-Stage N=279 | P | |
| Type of pull-through | ||||||||
| Soave | 851 (54.7) | 668 (55.6) | 183 (51.7) | <0.0001 | 313 (56.1) | 164 (58.9) | 149 (53.4) | <0.0001 |
| Duhamel | 91 (5.9) | 14 (1.2) | 77 (21.8) | 58 (10.4) | 2 (0.7) | 56 (20.1) | ||
| Other | 613 (39.4) | 519 (43.2) | 94 (26.6) | 187 (33.5) | 113 (40.5) | 74 (26.5) | ||
| Laparoscopic pull-through | 199 (12.8) | 184 (15.3) | 15 (4.2) | <0.0001 | 51 (9.1) | 40 (14.3) | 11 (3.9) | <0.0001 |
| Total LOS of initial surgical admission in days (median, IQR) | 12 (7, 18) | 11 (7, 17) | 12 (8, 20) | 0.001 | 12 (8, 18) | 11 (7, 17) | 12 (8, 20) | 0.02 |
| Transfusion received on day of pull-through | 30 (1.9) | 30 (2.5) | 15 (1) | 0.10 | 7 (1.3) | 7 (2.5) | 15 (5.0) | 0.13 |
| Additional operation through 2 years after pull-througha | 449 (28.9) | 312(26.0) | 137(38.7) | <0.0001 | 197 (35.3) | 84 (30.1) | 113(40.5) | 0.007 |
| Redo pull-througha | 170 (10.9) | 143 (11.9) | 27 (7.6) | 0.75 | 51 (9.1) | 30 (10.8) | 21 (7.5) | 0.61 |
| Anal dilationa | 47 (3.0) | 31 (2.6) | 16 (4.5) | 0.12 | 23 (4.1) | 9 (3.2) | 14 (5) | 0.27 |
| Any readmission through 2 years after pull-througha | 662 (42.6) | 455(37.9) | 207(58.5) | <0.0001 | 272 (48.7) | 107(38.4) | 165(59.1) | <0.0001 |
| Surgical Site Infectionb | 65 (4.2) | 32 (2.7) | 33 (9.3) | <0.0001 | 34 (6.1) | 9 (3.2) | 25 (9) | 0.007 |
| Anastomotic leakb | 65 (4.2) | 41 (3.4) | 24 (6.8) | 0.0005 | 38 (6.8) | 16 (5.7) | 22 (7.9) | 0.33 |
| Strictureb | 83 (5.3) | 67 (5.6) | 16 (4.5) | 0.34 | 32 (5.7) | 19 (6.8) | 13 (4.7) | 0.21 |
| Small Bowel Obstructionb | 82 (5.3) | 33 (2.8) | 49 (13.8) | <0.0001 | 45 (8.1) | 8 (2.9) | 37 (13.3) | <0.0001 |
| Enterocolitisc | 430 (27.7) | 309 (25.7) | 121 (34.2) | <0.0001 | 170 (30.5) | 72 (25.8) | 98 (35.1) | 0.003 |
a
Includes procedures performed or readmissions up to two years following the initial pull through procedure.
b
Diagnoses could occur at any admission, including the initial admission where HD was diagnosed.
c
Diagnoses only at admissions subsequent to the initial admission where HD was diagnosed.
PHIS: Pediatric Health Information System; LOS: length of stay; IQR: interquartile range; PS: propensity score