. Author manuscript; available in PMC: 2015 Nov 1.

Published in final edited form as: J Pediatr Surg. 2014 Aug 28;49(11):1614–1618. doi: 10.1016/j.jpedsurg.2014.04.011

Table 2.

Transmission disequilibrium tests of RET and NRG1 polymorphisms in HSCR.

Gene	Polymorphism (dbSNP ID)	Risk/Nonrisk allele	Risk allele transmissions (T/U)	Odds ratio (95% CI)	Transmission rate (τ)	TDT χ²	p
RET	rs2435357	T/C	24/1	24.0 (3.2–177.4)	0.96	21.2	4.2 × 10⁻⁶
NRG1	rs16879552	C/T	13/8	1.6 (0.7–3.9)	0.62	1.2	0.28
NRG1	rs7835688	C/G	17/10	1.7 (0.8–3.7)	0.63	1.8	0.18