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. 2013 Oct 19;53(12):1277–1285. doi: 10.1002/jcph.197

Table 2.

Summary of Patients With Serious Adverse Events Requiring Drug Discontinuation in This Study

Patient number Adverse events The day of drug discontinuation
Tolvaptan group
 Pt. #82 Hypernatremia Na 147 mEq/L 4th day
Carperitide group
 Pt. #3 Worsening heart failure Worsening pulmonary congestion 5th day
 Pt. #28 Hypotension SBP < 80 mmHg 1st day
 Pt. #32 Hypotension SBP < 80 mmHg 3rd day
 Pt. #43 Liver dysfunction AST 77 IU/L, ALT 179 IU/L 20th day
 Pt. #60 Hypotension SBP < 90 mmHg with general fatigue 2nd day
 Pt. #73 Hypotension SBP < 70 mmHg 2nd day
 Pt. #96 Hypotension SBP < 80 mmHg with dizziness 7th day

SBP, systolic blood pressure; AST, aspartate amino transferase; ALT, alanine transaminase.