Table 2.
Genes upregulated by the saiR mutation
| Microarray (fold induction) | RT-qPCR (fold induction) | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| locus | gene function | gene | ΔsaiR/wt | ΔspxA1ΔsaiR/ΔspxA1 | ΔsaiR/wt | ΔspxA1ΔsaiR/ΔspxA1 |
|
| ||||||
| BA3456 | transcription factor | spxA2 | 15.6 | 13.1 | 114.6±33.9 | 149.7±54.7 |
| BA3455 | hypothetical protein | 23.5 | 11.3 | 110.9±29.8 | 147.7±47.3 | |
| BA3454 | hypothetical protein | 30.1 | 22.8 | 111.8±25.6 | 132.4±40.5 | |
| BA3452 | Hypothetical protein | 49.2 | 44.6 | N/A | N/A | |
| BA0787 | major facilitator family | 2.0 | 13.9 | 1.6±0.2 | 3.8±1.4 | |
N/A: not applicable
Values in microarray are medians of triplicates and those in RT-qPCR are averages of triplicates with standard deviations. Locus is shown in B. anthracis Ames nomenclature used for microarray. BAS3453 is BAS3200 in B. anthracis Ames nomenclature.