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A. A consensus SH3-binding sequence APPAP was found in different primate TYMPs; and a core binding motif PxxP was also found in murine and other orders. B, C and D. Immunoprecipitation-immunoblotting assays were performed using indicated antibodies to determine the interaction of TYMP and Src family kinases including Lyn, Fyn, Src and Yes in human platelets.
