Table 1. Phosphopeptides showing Log2 SILAC H/L ratio greater than or equal to ±1.5 (∼2.8 fold higher or lower following resveratrol treatement)a.
| gene symbol | protein name | site 1 | site 2 | site 3 | resveratrol-induced fold change |
|---|---|---|---|---|---|
| AATF | Apoptosis antagonizing transcription factor | 316 | 320 | 321 | ↓3.23 |
| AFF4 | ALL1 fused gene from 5q31 family mem. 4 | 836 | ↓9.50 | ||
| AHSG | Alpha-2-HS-glycoprotein chain B | 204 | ↑25.00 | ||
| AKT1S1 | Proline-rich AKT1 substrate 1 | 266 | ↓13.84 | ||
| (PRAS40) | (246) | ||||
| AKT1S1 | Proline-rich AKT1 substrate 1 | 203 | ↓8.83 | ||
| (PRAS40) | (183) | ||||
| CRKRS | Cdc2-related kinase | 681 | 685 | ↑1.10 | |
| (CDK12) | |||||
| CRKRS | Cdc2-related kinase | 681 | ↓5.00 | ||
| (CDK12) | |||||
| EFTUD2 | Elongation factor Tu GTP-binding domain-containing protein 2 | 86 | ↑3.13 | ||
| ERC2 | ELKS/RAB6-interact./CAST family mem. 2 | 585 | 591 | ↓10.02 | |
| FOXA1 | Forkhead box protein A1 | 302 | ↑3.33 | ||
| FOXA1 | Forkhead box protein A1 | 308 | ↑1.32 | ||
| ITPR3 | Inositol 1,4,5-triphosphate receptor, type 3 | 934 | ↑1.92 | ||
| NCAPH | Non-SMC condensin I complex subunit H | 432 | ↑5.56 | ||
| NKX1-2 | NK1 transcription factor-rel. protein 2 | 60 | ↑8.33 | ||
| PHF14 | PHD finger protein 14 | 287 | 290 | ↑2.86 | |
| PLXDC2 | Plexin domain containing 2 | 506 | ↑3.03 | ||
| RFX2 | DNA binding regulatory factor X 2 | 652 | 654 | 656 | ↑7.14 |
| TLK2 | Tousled-like kinase 2 | 749 | ↑3.03 | ||
| TMPO | Thymopoietin | 351 | ↓10.92 | ||
| TP53 | Tumor protein p53 | 392 | ↑2.78 | ||
| ZC3HAV1 | CCCH-type zinc finger antiviral protein | 675 | ↑14.29 |
a
Indicated are gene symbol (with hyperlink to protein page at PhosphositePlus), protein name, phosphorylation site numbers and resveratrol-induced fold change (see Supporting Information Table 4 for additional information).