Table 2.
Demographic and Clinical Characteristics of Baseline (Year 5) Study Cohort by Apolipoprotein E Allele Status.a
| Characteristic | E4 (−/−)b, n = 1340 | E4 (+/−)b, n = 470 | E4 (+/+)b, n = 23 | P Value |
|---|---|---|---|---|
| Site | ||||
| Memphis | 598 (44.6) | 228 (48.5) | 10 (43.5) | .34 |
| Pittsburgh | 742 (55.4) | 242 (51.5) | 13 (56.5) | |
| Female | 687 (51.3) | 257 (54.7) | 11 (47.8) | .39 |
| Age, mean (SD), year | 77.5 (2.9) | 77.1 (2.7) | 76.5 (2.5) | .02 |
| Race | ||||
| White | 970 (72.4) | 276 (58.7) | 12 (52.2) | |
| Black | 370 (27.6) | 194 (41.3) | 11 (47.8) | <.001 |
| Diabetes | 241 (18.0) | 84 (17.9) | 3 (13.0) | .92 |
| Smoking | ||||
| Current | 73 (5.5) | 28 (6.0) | 0 (0) | .89 |
| Former | 667 (49.8) | 230 (48.9) | 11 (47.8) | |
| Never | 600 (44.8) | 212 (45.1) | 12 (52.2) | |
| Hypertension | 1043 (77.8) | 356 (75.7) | 18 (78.3) | .67 |
| Stroke | 113 (8.4) | 40 (8.5) | 0 (0) | .45 |
| Education | ||||
| Less than high school | 211 (15.8) | 93 (19.8) | 1 (4.4) | .03 |
| High school | 451 (33.7) | 173 (36.8) | 8 (34.8) | |
| Postsecondary | 678 (50.6) | 204 (43.4) | 14 (60.9) | |
| Total fasting cholesterol (SD), mg/dL year 1 | 202.3 (38.0) | 207.0 (38.9) | 215.7 (49.7) | .02 |
Abbreviations: SD, standard deviation; E4 (−/−), individuals with 0 E4 alleles; E4 (−/+), individuals with 1 E4 allele; E4 (+/+), individuals with 2 E4 alleles.
a Health, Aging and Body Composition Study; n = 1833.
b All values are expressed as N (%) of participants unless otherwise indicated.