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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Cancer Discov. 2014 Sep 24;4(12):1418–1429. doi: 10.1158/2159-8290.CD-14-0729

Figure 4. Activation of ERK and AKT in human melanoma cell lines is not codon-specific.

Figure 4

Shown are immunoblots for total and phosphorylated ERK (A), or AKT (B) in established human melanoma cell lines harboring the indicated NRAS mutations. Protein expression levels were quantified using LI-COR ImageStudio software. Each dot represents a single cell line. The mean is indicated by a line, and the standard error is shown as whiskers. * p<0.05