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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Phys Med Rehabil Clin N Am. 2015 Feb;26(1):57–67. doi: 10.1016/j.pmr.2014.09.005

Fig. 6.

Fig. 6

Fluorescence-activated cell sorting of several muscle mononuclear populations. (A) Whereas the percentage of other cell types such as mononuclear cells and inflammatory cells are unchanged in patients with CP, the fraction of satellite cells in CP muscle is half of what is found in TD muscle. (B) Immunohistochemical image of a satellite cell is shown in its native environment. Satellite cells are identified by looking for Pax7-positive staining (light green) on top of a cell nucleus (4′,6-diamidino-2-phenylindole [DAPI] positive; blue) that is located under the basal lamina (laminin staining; red). Satellite cells are indicated with white arrows. ([A] Data from Smith LR, Chambers HG, Lieber RL. Reduced satellite cell population may lead to contractures in children with cerebral palsy. Dev Med Child Neurol 2013;55(3):264–70; and [B] Courtesy of the National Skeletal Muscle Research Center, www.muscle.ucsd.edu; with permission.)