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. Author manuscript; available in PMC: 2015 Dec 4.
Published in final edited form as: Cell. 2014 Dec 4;159(6):1377–1388. doi: 10.1016/j.cell.2014.10.054

Figure 4. Sequence-based Localized Nucleosome Positioning.

Figure 4

(A) Heat map representing all pair-wise correlations (R) between NRLs and H3-linker occupancy levels at nucleosomes +1 through +6. Cyan and red represent negative and positive correlations, respectively. Calculations were based on nucleosomes at 3,194 genes longer than 1 kb (Table S2). NRL reports dyad-to-dyad distances in MNase-based maps (Zhang et al., 2011b). Similar observations were made with positions determined by ChlP-exo (not shown).

(B) Occupancy level of H3 ChlP-exo and SS/WW dinucleotide frequencies, relative to the midpoint between the +1 and +2 nucleosomes (Table S6), sorted by NRL between the +1 and +2 nucleosomes (Table S2).