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. 2014 Nov 30;33(1):98. doi: 10.1186/s13046-014-0098-1

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© Zhu et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Expression of Orai1 in glioma samples and glioma cell lines. (A) Representative patterns of Orai1 expression in non-neoplastic brain tissues and glioma samples of different grades by immunohistochemistry. NB, non-neoplastic brain tissues. Magnification, ×200. (B) Intensity scores for STIM1 and Orai1 expression by immunohistochemistry. The data are shown as mean ± standard deviation (SD). **P < 0.01 (WHO II vs. NB, WHO III–IV vs. NB, and WHO III–IV vs. WHO II). (C) Western blot analysis of Orai1 expression in non-neoplastic brain tissues, glioma samples (WHO II and IV), and five typical glioma cell lines. The gray values represent the means of three independent experiments (normalized to GAPDH expression).