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. 2014 Nov 25;11:193. doi: 10.1186/s12974-014-0193-4

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© Kułakowska et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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S1P concentration in blood plasma (A) and CSF (B) samples obtained from control (n =37) subjects and from patients with various inflammatory diseases of the CNS: MS (n =22), LNB (n =18), TBE (n =45). *Significantly different. Error bars represent standard error of the mean. S1P – sphingosine – 1– phosphate, CSF – cerebrospinal fluid, MS – multiple sclerosis, LNB – Lyme neuroborreliosis, TBE – tick borne encephalitis.