Table 2.
Estradiol groups in the entire population of patients and IVF outcome
| Variables | Group 1 < 2000 pg/mL, n = 123) | Group 2 (2000-4000) pg/ml, n = 288) | Group 3 > 4000 pg/mL, n = 78) | p- value |
|---|---|---|---|---|
| Age (years) | 32.6 ± 4.2 | 31.5 ± 4.1 | 30.6 ± 3.8 | <0.003 |
| BMI | 27.4 ± 7.0 | 26.3 ± 6.2 | 24.9 ± 6.1 | <0.024 |
| FSH dose (IU)* | 3851 ± 1454 | 2883 ± 1314 | 1900 ± 896 | <0.001 |
| Peak estradiol (pg/mL) | 1489 ± 365 | 2950.1 ± 561 | 4758 ± 594 | <0.001 |
| Oocytes retrieved | 11.9 ± 5.7 | 19.9 ± 7.5 | 26.5 ± 8.6 | <0.001 |
| MII oocytes | 8.9 ± 4.7 | 15.1 ± 6.3 | 20.7 ± 7.3 | <0.001 |
| Total 2PN | 6.4 ± 3.7 | 10.3 ± 4.7 | 13.5 ± 5.9 | <0.001 |
| AEQS | 1.78 ± 0.67 | 1.57 ± 0.58 | 1.48 ± 0.44 | <0.001 |
| No. embryos transferred | 2.11 ± 0.50 | 2.04 ± 0.40 | 1.92 ± 0.35 | <0.008 |
| BCP (%) | 58.5a | 70.8b | 78.2b | <0.007 |
| CP (%) | 49.6a | 64.2b | 65.4b | <0.015 |
| LB (%) | 47.2 | 59.0 | 61.5 | 0.052 |
| Total pregnancy loss (%) | 19.4 | 16.7 | 21.3 | 0.670 |
| Poor quality embryos for transfer (%) | 19.5 | 9.7 | 1.3 | <0.001 |
Mean ± 1SD.
Chi-square and ANOVA tests as appropriate. For pregnancy related variables, within row, response variables with different superscripts differ at a minimum of P < 0.05. The number patients in the entire population were 489. *The n for FSH dose was 470 due to missing values.