Table II.

True (toxicity, efficacy) probabilities for scenarios 1–6 for nine treatment combinations.

Scenario	Doses of A	True (toxicity, efficacy) rates
		Doses of B
		1	2	3
1	3	(0.08, 0.15)	(0.10, 0.20)	(0.18, 0.40)
	2	(0.04, 0.10)	(0.06, 0.16)	(0.08, 0.20)
	1	(0.02, 0.05)	(0.04, 0.10)	(0.06, 0.15)
2	3	(0.16, 0.20)	(0.25, 0.35)	(0.35, 0.50)
	2	(0.10, 0.10)	(0.14, 0.25)	(0.20, 0.40)
	1	(0.06, 0.05)	(0.08, 0.10)	(0.12, 0.20)
3	3	(0.24, 0.40)	(0.33, 0.50)	(0.40, 0.60)
	2	(0.16, 0.20)	(0.22, 0.40)	(0.35, 0.50)
	1	(0.08, 0.10)	(0.14, 0.25)	(0.20, 0.35)
4	3	(0.33, 0.50)	(0.40, 0.60)	(0.55, 0.70)
	2	(0.18, 0.35)	(0.25, 0.45)	(0.42, 0.55)
	1	(0.12, 0.20)	(0.20, 0.40)	(0.35, 0.50)
5	3	(0.45, 0.55)	(0.55, 0.65)	(0.75, 0.75)
	2	(0.20, 0.36)	(0.35, 0.49)	(0.40, 0.62)
	1	(0.15, 0.20)	(0.20, 0.35)	(0.25, 0.50)
6	3	(0.65, 0.60)	(0.80, 0.65)	(0.85, 0.70)
	2	(0.55, 0.55)	(0.70, 0.60)	(0.75, 0.65)
	1	(0.50, 0.50)	(0.55, 0.55)	(0.65, 0.60)

Combinations with acceptable toxicity (i.e., ≤ ϕ_T = 30%) and high efficacy (i.e., ≥ ϕ_E = 30%) are defined as ‘binations’ and are indicated in boldface type.