Table V.

True (toxicity, efficacy) probabilities for scenarios 1–9 for six treatment combinations.

Scenario	Doses of A	True (toxicity, efficacy) rates
		Doses of B
		1	2	3
1	2	(0.10, 0.20)	(0.15, 0.40)	(0.45, 0.60)
	1	(0.05, 0.10)	(0.15, 0.30)	(0.20, 0.50)
2	2	(0.10, 0.20)	(0.20, 0.40)	(0.50, 0.55)
	1	(0.05, 0.10)	(0.15, 0.30)	(0.40, 0.50)
3	2	(0.10, 0.20)	(0.15, 0.30)	(0.20, 0.50)
	1	(0.05, 0.10)	(0.10, 0.20)	(0.15, 0.40)
4	2	(0.10, 0.30)	(0.40, 0.50)	(0.60, 0.60)
	1	(0.05, 0.20)	(0.20, 0.40)	(0.50, 0.55)
5	2	(0.10, 0.20)	(0.20, 0.40)	(0.50, 0.50)
	1	(0.05, 0.10)	(0.15, 0.30)	(0.20, 0.40)
6	2	(0.40, 0.44)	(0.72, 0.58)	(0.90, 0.71)
	1	(0.23, 0.36)	(0.40, 0.49)	(0.59, 0.62)
7	2	(0.24, 0.40)	(0.56, 0.60)	(0.83, 0.78)
	1	(0.13, 0.32)	(0.25, 0.50)	(0.42, 0.68)
8	2	(0.15, 0.30)	(0.25, 0.41)	(0.40, 0.54)
	1	(0.11, 0.15)	(0.15, 0.22)	(0.20, 0.31)
9	2	(0.15, 0.17)	(0.19, 0.33)	(0.23, 0.55)
	1	(0.12, 0.10)	(0.15, 0.22)	(0.19, 0.39)

Combinations with acceptable toxicity (i.e., ≤ ϕ_T = 30%) and high efficacy (i.e., ≥ ϕ_E = 20%) are defined as ‘target combinations’ and are indicated in boldface type.