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. Author manuscript; available in PMC: 2015 Dec 15.
Published in final edited form as: J Immunol. 2014 Nov 5;193(12):6050–6060. doi: 10.4049/jimmunol.1401746

Figure 3. Bone marrow derived macrophages (BMDM) reveal Bbaa1 regulates the magnitude of the IFN response to B. burgdorferi.

Figure 3

RT-PCR analysis of transcripts in BMDM from B6, C3H, B6.C3-Bba1 and C3.B6-Bbaa1 mice treated with media, sonicated B. burgdorferi (sonicate) or living B. burgdorferi (B. burgdorferi) for 6 hours. Transcript levels for Ifnβ, Gbp2, Cxcl9, Cxcl10, Iigp, and Tnfα were normalized to β-actin. Data are averages ± SE, with trends representative of 5 separate experiments. Significance determined by ANOVA, with Bonferroni post-hoc comparison, shown for ISCL with appropriate background parental strain. Differences between B6 and C3H for Ifnβ, Gbp2, Cxcl9, Cxcl10, and Iigp were also significant (not shown).