. 2014 Nov 28;6:195–204. doi: 10.2147/CPAA.S71574

Table 4.

Test/reference geometric LS mean total exposure (AUC_0–t) treatment ratios and 90% CI of R-(+)- and S-(−)-ALA enantiomers by treatment.

R-(+) AUC ratios LS and CI				S-(−) AUC ratios LS and CI
Treatment	Geometric mean (ng · h · mL⁻¹)	90% CI		Geometric mean (ng · h · mL⁻¹)	90% CI
Treatment	Geometric mean (ng · h · mL⁻¹)	Lower	Upper	Geometric mean (ng · h · mL⁻¹)	Lower	Upper
T 200/OS	69.44	60.66	79.49	74.52	66.19	83.91
T 300/OS	79.36	69.99	89.99	85.66	76.25	96.22
T 600/OS	64.27	57.93	71.31	67.47	61.23	74.35

Abbreviations: ALA, alpha-lipoic acid; AUC, area under the curve; LS, least squares; CI, confidence interval; T 200, 200 mg tablet; OS, orally administered ALA solution; T 300, 300 mg tablet; T 600, 600 mg tablet.