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Survival of Cynomolgus Macaques after Intravenous Challenge with Vegetative Bacilli of the Ames Strain and Each of the Toxin Deletion Mutants
| Log10 dose (range) | Surviving animals by strain (no. surviving/no. challenged) |
|||
|---|---|---|---|---|
| Ames | EF− | LF− | PA− | |
| 3–4 | ND | 0/1 | ND | ND |
| 4–5 | 0/1 | 0/2 | 3/3 | ND |
| 5–6 | 0/1 | ND | ND | ND |
| 6–7 | 0/1 | ND | 0/2 | 2/2 |
| 7–8 | ND | ND | 0/1 | 0/1 |
ND, not done.
