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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Prog Lipid Res. 2014 Jun 30;0:1–18. doi: 10.1016/j.plipres.2014.06.002

Fig. 7.

Fig. 7

Schematic presentation of the specific interaction between anionic PS and basic residues in Akt and PDK1. The basic residues R466/K467 and R15/K20 that bind to PS (red circles) are located near the PIP3 binding pocket in PDK1 and Akt, respectively. K419 and K420 are located in the regulatory domain of Akt.