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Histopathologic examination of the colonic tissue (× 100). Hematoxylin and eosin staining of colon tissues from A: Wild type (WT); B: WT challenged with Clostridium difficile (C. difficile); C: Interleukin 10-deficient (IL-10-/-); D: IL-10-/- challenged with C. difficile; E: Quantification of colitis severity. Error bars indicate standard error of the mean; aP < 0.05 vs untreated.
