Table 1.
General overview of MDSC phenotype.
| Species | Disease/condition | Markers | MDSC subtypes | Reference |
|---|---|---|---|---|
| Murine | MM | CD11b+GR1+ | Ly6Glow or MO-MDSC | (10, 21, 22) |
| Lymphoma | Ly6Ghigh or G-MDSC | |||
| Leukemia | ||||
| Human | MM | CD11b+CD33+ | CD14+HLA-DR−/low or MO-MDSC | (23) |
| CD14−CD15+ or G-MDSC | (12, 22) | |||
| Lymphoma | – | CD14+HLA-DRlow | (14) | |
| Leukemia | CD11b+CD33+ | CD14−HLA-DR (AML) | (24) | |
| CD14−arginase-1+ (CML) | (25) | |||
| CD14+HLA-DRlow (CLL) | (13) | |||
| Allo-HSCT | – | CD14+HLA-DRlow | (26) |
Markers described to characterize murine and human MDSC in multiple myeloma (MM), lymphoma, leukemia and allogeneic hematopoietic stem cell transplantation (Allo-HSCT).