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IL-33 polarizes M2 macrophages. A-C, Numbers of macrophages (Fig 5, A), CD206+ M2 macrophages (Fig 5, B), and IL-33+ M2 macrophages (Fig 5, C). D, Lung tissue Arg1 and Nos2 mRNA expression. E, BMDMs were stimulated with IL-13, IL-33, and bleomycin (BLM; alone or together). Arg1 and Nos2 mRNA expression was quantified. Vertical bars = SEMs (n = 5 mice per group per experiment). *P < .05 compared with PBS and #P < .05 compared with WT values. Data are pooled from 3 experiments.
