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. 2014 Dec;99(12):1792–1798. doi: 10.3324/haematol.2014.111195

Figure 2.

Figure 2.

Enforced expression of RPS19 rescues the lethal bone marrow failure in Rps19-deficient mice. (A) Experimental strategy to validate the therapeutic potential of RPS19 gene correction. (B) Erythrocyte number, hemoglobin concentration, mean corpuscular volume (MCV), reticulocyte number, white blood cell number and platelet number on day 14 after doxycycline administration (n = 23, 24, 16, 16, 10 and 11 for the Control SFFV-GFP, Control SFFV-RPS19, D/+ SFFV-GFP, D/+ SFFV-RPS19, D/D SFFV-GFP and D/D SFFV-RPS19, respectively). Error bars represent standard deviation.