Table 2.
Multivariable regression analyses of the association between hepatitis C viral infection (HCV), pregnancy number and hepatocellular carcinoma among Egyptian women
| Variable | Adjusted OR (95% CI)* |
|---|---|
| Model 1 | |
| HCV infection | |
| No | Reference |
| Yes | 13.50 (8.09-22.53) |
| Model 2 | |
| Pregnancy number | |
| ≤ 5 pregnancies | Reference |
| > 5 pregnancies | 1.84 (1.17-2.89) |
| Model 3 | |
| HCV infection among women with ≤ 5 pregnancies | |
| No | Reference |
| Yes | 6.57 (3.04-14.25) |
| HCV infection among women with > 5 pregnancies | |
| No | Reference |
| Yes | 21.42 (10.43-44.00) |
| Pregnancy number among women without HCV infection | |
| ≤ 5 pregnancies | Reference |
| > 5 pregnancies | 0.72 (0.30-1.73) |
| Pregnancy number among women with HCV infection | |
| ≤ 5 pregnancies | Reference |
| > 5 pregnancies | 2.33 (1.29-4.22) |
| Dichotomized Pregnancy number * HCV interaction | |
| p-value | 0.02 |
*Adjusted odds ratio (95% confidence interval); All models were adjusted for age, birthplace, education, and HBV infection.
Model 1 included HCV infection as the main variable with the adjustment covariates.
Model 2 included dichotomized pregnancy number (≤ 5 versus > 5) as the main variable with the adjustment covariates.
Model 3 included both HCV infection and dichotomized pregnancy number, and the interaction term dichotomized Pregnancy number*HCV interaction, in addition to the adjustment covariates.