Table 3.
Univariate Model | Multivariable base model (R2 = 0.38) | Multivariable model 2 (R2 = 0.50) | |||||||
---|---|---|---|---|---|---|---|---|---|
| |||||||||
coeff. | SE | p-value | coeff. | SE | p-value | coeff. | SE | p-value | |
|
|||||||||
CGD | −0.11 | 0.03 | <0.001 | −0.13 | 0.02 | <0.001 | −0.14 | 0.03 | <0.001 |
age | 0.001 | 0.002 | 0.56 | 0.002 | 0.001 | 0.23 | 0.001 | 0.001 | 0.70 |
male gender | 0.05 | 0.03 | 0.09 | 0.08 | 0.02 | 0.002 | 0.06 | 0.03 | 0.02 |
hypertension | 0.03 | 0.03 | 0.36 | 0.09 | 0.03 | 0.01 | |||
smoking | −0.02 | 0.03 | 0.48 | −0.002 | 0.03 | 0.94 | |||
family history | −0.01 | 0.03 | 0.81 | 0.04 | 0.03 | 0.09 | |||
LDL | 0.08×10−3 | 0.48 ×10−3 | 0.87 | 0.05×10−3 | 0.4×10−3 | 0.90 | |||
HDL | 2.0×10−3 | 0.8×10−3 | 0.02 | 1.0×10−3 | 1.0×10−3 | 0.31 | |||
hsCRP | −0.0×10−3 | 1.5×10−3 | 0.55 | ||||||
oxidized LDL | −0.6×10−3 | 0.4×10−3 | 0.11 | ||||||
lactoferrin | −26×10−6 | 19×10−6 | 0.17 | ||||||
MPO | −39×10−6 | 20×10−6 | 0.053 | ||||||
MMP-9 | −32×10−6 | 39×10−6 | 0.40 | ||||||
TNF-α | −0.2×10−6 | 0.1×10−6 | 0.08 | ||||||
GM-CSF | 1.6×10−3 | 3.4×10−3 | 0.64 | ||||||
IL-1β | −2.2×10−3 | 3.9×10−3 | 0.57 | ||||||
IL-6 | 3.4×10−3 | 1.3×10−3 | 0.01 | ||||||
IL-10 | 1.7×10−3 | 0.5×10−3 | 0.002 | ||||||
IL-12p70 | 0.4×10−3 | 0.1×10−3 | 0.002 | ||||||
IL-13 | 0.3×10−3 | 0.1×10−3 | 0.002 | ||||||
IL-17 | 0.5×10−3 | 0.8×10−3 | 0.58 | ||||||
CCL3 (MIP-1α) | −0.3×10−3 | 0.4×10−3 | 0.43 | ||||||
CCL4 (MIP-1β) | 0.4×10−6 | 72×10−6 | 0.99 | ||||||
CCL5 RANTES | −0.7×10−6 | 0.8×10−6 | 0.37 | ||||||
CXCL8 (IL-8) | −0.3×10−3 | 0.4×10−3 | 0.50 | ||||||
TNFR1 | 4×10−6 | 7×10−6 | 0.54 | ||||||
TNFR2 | −8×10−6 | 8×10−6 | 0.29 | ||||||
IL-6R | 2×10−6 | 3×10−6 | 0.43 |
Coeff is the estimated regression coefficient. SE is the variance of the estimated regression coefficient.