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. Author manuscript; available in PMC: 2015 Dec 2.
Published in final edited form as: Circulation. 2014 Sep 19;130(23):2031–2039. doi: 10.1161/CIRCULATIONAHA.113.006824

Table 3.

Internal Carotid Arterial Wall Volume in Univariate and Multivariable Linear Regression Analyses

Univariate Model Multivariable base model (R2 = 0.38) Multivariable model 2 (R2 = 0.50)

coeff. SE p-value coeff. SE p-value coeff. SE p-value

CGD −0.11 0.03 <0.001 −0.13 0.02 <0.001 −0.14 0.03 <0.001
age 0.001 0.002 0.56 0.002 0.001 0.23 0.001 0.001 0.70
male gender 0.05 0.03 0.09 0.08 0.02 0.002 0.06 0.03 0.02
hypertension 0.03 0.03 0.36 0.09 0.03 0.01
smoking −0.02 0.03 0.48 −0.002 0.03 0.94
family history −0.01 0.03 0.81 0.04 0.03 0.09
LDL 0.08×10−3 0.48 ×10−3 0.87 0.05×10−3 0.4×10−3 0.90
HDL 2.0×10−3 0.8×10−3 0.02 1.0×10−3 1.0×10−3 0.31
hsCRP −0.0×10−3 1.5×10−3 0.55
oxidized LDL −0.6×10−3 0.4×10−3 0.11
lactoferrin −26×10−6 19×10−6 0.17
MPO −39×10−6 20×10−6 0.053
MMP-9 −32×10−6 39×10−6 0.40
TNF-α −0.2×10−6 0.1×10−6 0.08
GM-CSF 1.6×10−3 3.4×10−3 0.64
IL-1β −2.2×10−3 3.9×10−3 0.57
IL-6 3.4×10−3 1.3×10−3 0.01
IL-10 1.7×10−3 0.5×10−3 0.002
IL-12p70 0.4×10−3 0.1×10−3 0.002
IL-13 0.3×10−3 0.1×10−3 0.002
IL-17 0.5×10−3 0.8×10−3 0.58
CCL3 (MIP-1α) −0.3×10−3 0.4×10−3 0.43
CCL4 (MIP-1β) 0.4×10−6 72×10−6 0.99
CCL5 RANTES −0.7×10−6 0.8×10−6 0.37
CXCL8 (IL-8) −0.3×10−3 0.4×10−3 0.50
TNFR1 4×10−6 7×10−6 0.54
TNFR2 −8×10−6 8×10−6 0.29
IL-6R 2×10−6 3×10−6 0.43

Coeff is the estimated regression coefficient. SE is the variance of the estimated regression coefficient.