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. Author manuscript; available in PMC: 2016 Jan 1.

Published in final edited form as: Virology. 2014 Nov 19;0:174–180. doi: 10.1016/j.virol.2014.10.025

Fig. 4 — Groups of mice were immunized i.m. in the gastrocnemious with 10²–10⁵ ffu of GASGAS or GASγ followed by i.c. challenge with 10³ ffu of DRV4 13 days later. They were monitored for mortality and morbidity for 28 days post-challenge. A is a summary of the survival proportions while B shows the survival curves. An ED₅₀ comparison of GASGAS and GASγ is shown in C. Significant difference between survival curves was determined by the Mantel-Cox test. *, p≤0.05 and denotes the difference between the GASγ curve and the GASGAS curve at the same immunization dosage. ■, 10² ffu; , 10³ ffu; ♦, 10⁴ ffu; ●, 10⁵ ffu; ◊, non-immunized control.

Inline graphic — Groups of mice were immunized i.m. in the gastrocnemious with 10²–10⁵ ffu of GASGAS or GASγ followed by i.c. challenge with 10³ ffu of DRV4 13 days later. They were monitored for mortality and morbidity for 28 days post-challenge. A is a summary of the survival proportions while B shows the survival curves. An ED₅₀ comparison of GASGAS and GASγ is shown in C. Significant difference between survival curves was determined by the Mantel-Cox test. *, p≤0.05 and denotes the difference between the GASγ curve and the GASGAS curve at the same immunization dosage. ■, 10² ffu; , 10³ ffu; ♦, 10⁴ ffu; ●, 10⁵ ffu; ◊, non-immunized control.