Table 3.
Upregulated gene expression of negative pressure wound therapy with instillation (NPWTi-d)
| Upregulated | |||
|---|---|---|---|
| Gene symbol | Gene name | Fold change | Functional gene grouping |
| CSF2 | Colony stimulating factor 2 (granulocyte macrophage) | 4.04 | Growth factor |
| CXCL2 | Chemokine (C-X-C motif) ligand 2 | 3.54 | Inflammatory cytokines and chemokines |
| IL-1a | Interleukin 1, alpha | 7.57 | Inflammatory cytokines and chemokines |
| MMP9 | Matrix metallopeptidase 9 | 55.93 | Remodeling enzyme |
| TNC | Tenascin C | 9.26 | Cellular adhesion |
Differentially expressed genes greater than 2; P < .05.