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. 2014 Dec 3;14:904. doi: 10.1186/1471-2407-14-904

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© Yan et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of upregulation of E2F1 on cell pump rate of doxorubicin, cell cycle, and apoptotic rate in SGC7901/DDP cells. A: IC50 values for anticancer drugs in SGC7901/DDP cells; B, C: Pump rate of doxorubicin in SGC7901/DDP cells stably expressing E2F1 was analyzed by flow cytometry; D, E: Percentages of apoptotic cells were analyzed by flow cytometry. F: Cell cycle of SGC7901/DDP cells after E2F1 gene transfection was analyzed by flow cytometry. All values are mean ± SE. ^* P < 0.05 for E2F1 group versus GFP group and NC group.